Protocol
:: Regional Centres



The St. Johnís Centre is located at:

L.A. Miller Centre
Southcott Hall, Room 516
100 Forest Rd.
St.Johnís, NL
A1A 1E5

Tel.: (709) 777-6270

Study Staff


Dr. Carol Joyce
Centre Director

Dr. Christopher Kovacs
Centre Co-Director

Dr. Peter Collingwood : Radiologist
Dr. Peter Hollett : Radiologist
:: Participants

Men and women, aged 25 years and older, recruited from 1995 to 1997, residing within a 50 km radius of one of nine designated clinical centres, contacted at random by phone.

Youth cohort: men and women, aged 16-24 recruited from 2004-2006.


:: Data Collection

At baseline, year 3 (for participants 40-60), year 5, year 10 and year 16 (for participants 60-75), a long questionnaire was administered to all consenting participants. A follow up mailed questionnaire was completed annually. Self reported fractures were confirmed by medical report or hospital discharge.

Bone density was measured using DXA (dual-energy X-ray absorptiometry) at the lumbar spine and hip, and ultrasound of the shin and wrist were taken.

Participants aged 50 years and older have had radiographs taken of the thoracic and lumbar spine. Blood, urine and DNA samples have been collected from participants in some centers at baseline, year 5 and year 10 follow-up. At year 16 follow-up, the participants aged 60 to 75 had radiographs taken of the thoracic and lumbar spine. Blood and DNA samples were collected from all consenting participants.